Sample collection and
interpreting results

Fetal fibronectin (fFN) testing can help you manage preterm birth effectively, without compromising clinical outcomes. The Rapid fFN® test returns either a positive or negative result, enabling you to manage care for your patients accordingly.1

In-Service presentation

For new nurses and residents, or just for a refresher, a recorded Rapid fFN in-service presentation is accessible at your convenience. The presentation is approximately 15 minutes long, and also includes a quick 5-question true/false quiz at the end to test your knowledge.

How to collect an fFN specimen2

Collect specimen prior to digital examination or manipulation of the cervix to avoid sample contamination.

Step 1

During speculum exam, lightly rotate swab across posterior fornix of the vagina for 10 seconds to absorb cervicovaginal secretions.

Step 2

Remove swab and immerse tip in buffer. Break the shaft at the score even with the top of the tube.

Step 3

Align the shaft with the hole inside the tube cap and push down tightly over shaft, sealing tube; ensure shaft is aligned to avoid leakage. Send fetal fibronectin sample to a lab near you.

For accurate results, be sure to follow these instructions and see package insert:

  • The specimen should be collected prior to a digital cervical exam, collection of culture specimens or vaginal probe ultrasound exams.
  • Do not contaminate the swab or specimen with lubricant, soaps, disinfectants or creams.
  • Do not test if patient has moderate or gross vaginal bleeding, advanced cervical dilation (3 cm or greater), rupture of membranes or suspected or known placental abruption or placenta previa.
  • If patient has had sex in the prior 24 hours:
    • A negative result is still valid
    • A positive result may not be valid and should be confirmed > 24 hours

Order FREE specimen collection kits, patients brochures and others materials below.

Interpreting results of the fetal fibronectin test

Negative results

A negative Rapid fFN test result has a reliably high negative predictive value (NPV) which can help rule out imminent preterm labor.

Negative Test Icon

NPV for delivery within:

7 days = 99.5%
14 days = 99.2%
Less than 37 weeks = 84.5%

A negative Rapid fFN test result offers benefits that include the opportunity to better manage resources and optimize the administration of steroids.

Positive results

A positive Rapid fFN test result indicates that some type of disruption is occurring with the pregnancy. While only 13% of patients with positive Rapid fFN test result will deliver in the next 7 days, almost half will deliver before 37 weeks.1

Positive Test Icon

PPV for delivery within:

7 days = 12.7%
14 days = 16.7%
Less than 37 weeks = 44.7%

A positive Rapid fFN test result offers multiple benefits, including opportunities to better manage care for patients who are at increased risk and optimize the administration of steroids.

Interpreting results in asymptomatic patients1

The Rapid fFN test is also indicated for use in asymptomatic patients during routine prenatal visits between 220 and 306 weeks of gestation in women with a singleton gestation.

In studies on asymptomatic patients:

  • NPVs ranged from 96.4%–97.9% depending on the gestational week of collection, making it highly likely that delivery will not occur before 346 weeks of gestation.
  • PPVs ranged from 13.3%–31.7% and represent an approximate 4- to 7-fold increase in risk over the reliability of predicting delivery in the absence of fFN test information.
  • NPVs and PPVs varied depending on gestational week collected (24, 26, 28, & 30 weeks) and endpoint (286 or 346 weeks).

For more information on asymptomatic testing, see the package insert.

Predict preterm labor with safe, non-invasive fFN testing.

Contact us for more information about the Rapid fFN® test.