Delivering Predictive Value Beyond Risk Factors or Symptoms

Preterm birth risk can be assessed by symptoms of labor such as contractions, and vaginal bleeding. But these biophysical markers are not as accurate in predicting preterm birth as fetal fibronectin, a biochemical marker that can often be detected before the biophysical markers.

NIH preterm prediction study: Risk factors for preterm birth1

Fetal fibronectin is one of the most powerful predictors of preterm birth before 32 weeks.1


  1. Goldenberg RL, Iams JD, Mercer BM, et al. The Preterm Prediction Study: the value of new vs standard risk factors in prediction early and all spontaneous preterm births. Am J Public Health. 1998;88:233-238.

NIH Study

The role of fetal fibronectin in preterm birth

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